Secretory microRNA-29 in Gingival Crevicular Fluid during Canine Retraction
نویسندگان
چکیده
Introduction: Gingival crevicular fluid (GCF) has been widely investigated as a potential source of biomarkers for an individual’s oral and general health information. Various molecules presented in GCF were reported as potential biomarkers for orthodontic tooth movement (OTM). MicroRNAs (miRNAs) are small non-coding RNAs that are involved in post-transcriptional gene regulation. Recently, secretory miRNAs are being investigated as diagnostic as well as therapeutic tools. In this study, we investigated secretory miRNA-29 as a potential biomarker for detection of periodontal remodeling during OTM. The aim of the study was to confirm the presence of secretory miRNAs in GCF and investigate the temporal expression profiles of secretory miRNA-29 during canine retraction.
منابع مشابه
Secretory microRNA-29 expression in gingival crevicular fluid during orthodontic tooth movement
Secretory microRNAs (miRNAs) have been used increasingly as biomarkers for cancers, autoimmune diseases and inflammatory diseases. They are reported as being freely circulated or encapsulated in microvesicles such as exosomes. This study was performed to elucidate the presence of miRNAs with exosomes in human gingival crevicular fluid (GCF), and the expression profile of miRNA-29 during orthodo...
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